Table 5 Changes in particle sizes of single- and double-layers resveratrol nanoemulsions prepared by complex coacervation during storage for 28 days

Sample	Storage (day)
	0	1	3	5	7	14	21	28	F-value
	SLRN1)	5)^B27.09±2.042)^d4)	^B29.48±3.71^cd	^C29.89±1.70^cd	^B35.7±2.33^bc	^B41.30±1.40^b	^B42.70±3.47^b	^B56.60±7.90^a	^C51.90±7.77^a	17.3^***
CN	^A45.60±11.89^d	^B50.87±0.40^d	^B70.00±19.75^cd	^AB53.70±26.31^d	^A99.80±26.36^bc	^A115.40±22.44^ab	^A144.30±19.46^a	^B105.00±28.20^bc	8.56^***
AN	^A55.40±14.27^c	^A133.90±39.16^ab	^A150.40±26.21^a	^A94.00±37.17^bc	^A116.40±35.54^ab	^A115.50±20.40^ab	^A152.30±4.52^a	^A166.50±38.57^a	4.48^**
CYN	^B26.85±1.99^d	^B33.00±3.63^cd	^C38.20±6.26^bc	^B28.39±2.97^d	^B38.20±5.32^bc	^B41.80±3.62^ab	^B42.70±3.25^ab	^C45.90±5.20^a	7.88^**
F-value	6.79^*3)	18.45^***	32.4^***	4.96^*	9.70^**	22.71^***	83.52^***	15.96^**

SLRN: single-layer resveratrol nanoemulsion based on water, CN: double-layers resveratrol nanoemulsion prepared by complex coaervation with chitosan, AN: double-layers resveratrol nanoemulsion prepared by complex coaervation with alginate, CYN: double-layers resveratrol nanoemulsion prepared by complex coaervation with β-cyclodextrin
Mean±SD
^***: p<0.001, ^**: p<0.01, ^*: p<0.05
^a-d: Means with different superscripts in the same column differ significantly at p<0.05 by Duncan’s multiple range test
^A-C: Means with different superscripts in the same column differ significantly at p<0.05 by Duncan’s multiple range test