Table 4 Changes in particle size of single-layer resveratrol nanoemulsions formed by self-assembly during storage 28 days

Composition ratio	Storage (day)
	Mixture:Water	0	1	3	7	14	21	28	F-value
	Res+MCTs:T =1:11)	0.5:99.5	5)^D136.00±10.782)	^C149.20±23.87	^D155.70±7.50	^D113.00±19.14	^D134.60±20.30	^C147.90±8.32	^D148.70±15.42	1.86^n.s.
1:99		^D154.90±22.94	^C168.60±34.68	^D138.80±20.13	^D131.40±10.10	^D123.40±3.61	^C138.80±26.54	^D163.30±7.67	1.94^n.s.
3:97		^D176.40±64.12	^C177.20±23.82	^CD191.70±29.03	^D150.00±20.37	^D147.00±41.26	^C174.20±21.67	^CD183.00±9.54	0.63^n.s.
5:95		^C250.60±9.26 ^b	^B323.00±11.36^a	^BC216.70±40.60^b	^C212.80±13.33^b	^C210.30±25.69 ^b	^B236.00±36.72 ^b	^BC252.20±36.48^b	5.01 **
10:90		^B342.00±47.49	^B361.00±29.82	^B269.20±52.82	^B297.40±26.23	^B321.00±33.34	^B283.50±35.62	^B305.00±10.53	2.18^n.s.
20:80		^A655.00±36.76^ab4)	^A696.00±49.00^a	^A568.00±41.07^bc	^A528.00±39.69^c	^A589.00±36.61^bc	^A424.00±37.07^d	^A632.00±93.31^ab	7.07^**
F-value		81.94^***3)	134.37^***	61.53^***	88.51^***	74.14^***	40.21^***	37.60^***
Res+MCTs:T =1:2		0.5:99.5	^C26.47±1.11^cd	^C40.20±9.31^ab	^C20.28±0.81^d	^C31.20±2.32^bcd	^D35.40±1.01^bc	^C50.30±16.45^a	^D31.20±0.37^bcd	46.12^***
	1:99	^C25.30±2.15^b	^C50.70±18.42^a	^C26.91±2.32^b	^C41.30±1.01^a	^D47.80±3.41^a	^C44.60±3.86^a	^D47.90±1.64^a	5.46^**
	3:97	^C24.00±0.99^e	^C26.34±0.34^e	^C32.70±1.10^d	^C39.30±2.19^c	^D45.80±5.03^b	^C51.70±3.78^ab	^CD55.60±2.29^a	60.39^***
	5:95	^C30.00±4.65^e	^C44.60±10.19^d	^C42.90±2.97^d	^C60.40±1.61^c	^C63.00±11.06^bc	^C72.60±8.73^ab	^C82.20±6.50^a	19.51
	10:90	^B169.90±42.64	^B212.80±63.40	^B229.90±29.82	^B174.20±39.85	^B235.50±4.38	^B178.90±32.81	^B217.20±17.43	1.46^n.s.
	20:80	^A700.00±34.70^b	^A799.00±57.30^a	^A661.00±52.05^bc	^A558.00±32.30^d	^A 603.00±16.87^cd	^A447.00±36.50^e	^A582.00±27.43^d	23.00^***
	F-value	428.40^***	211.86^***	320.23^***	193.98^***	2444.14^***	161.87^***	492.12^***
	Res+MCTs:T =1:3	0.5:99.5	^C8.77±0.18^b	^A18.96±0.36^b	^E11.34±0.10^b	^B24.07±0.10^b	^D20.26±0.38^b	^C24.89±1.15^b	^B118.60±56.06^a	31.44^***
1:99		^A13.86±0.14^d	^B17.40±0.10^c	^D13.11±0.12^d	^B22.89±0.03^ab	^CD22.72±0.39^ab	^C23.58±0.60^a	^D22.11±12.92^b	192.79^***
3:97		^A13.92±0.07^d	^DE15.81±0.06^c	^CD14.26±0.02^d	^B22.94±0.24^b	^CD24.25±1.09^a	^C25.47±0.77^a	^D24.34±13.85^a	128.90^***
5:95		^A14.17±0.12^e	^E15.58±0.11^d	^C14.89±0.12^de	^B23.26±0.24^c	^C25.66±1.38 ^b	^C28.75±1.17 ^a	^D 26.58±15.26 ^b	172.22^***
10:90		^B12.39±0.66^f	^CD16.52±0.30^e	^B16.54±0.33^e	^B23.82±0.30^d	^B35.70±1.56^c	^B45.20±3.67^b	^C49.70±25.96^a	122.39^***
20:80		^C9.04±0.57^d	^BC16.95±0.93^d	^A17.97±1.93^d	^A91.10±2.34^c	^A127.80±4.71^b	^A120.10±10.03^b	^A151.30±75.21^a	299.81^***
F-value		142.09^***	24.36^***	25.99^***	1606.13^***	753.23^***	218.69^***	49.82^***

Res+MCTs:T=1:1 : resveratrol+medium-chain riaylglycerols:Tween^®80=1:1, 2) Mixture:Water : Resveratrol+MCTs+Tween^®80:Water
Mean±SD
^***: p<0.001, ^**: p<0.01, n.s.: not significantly
^a-f: Means with different superscripts in the same column differ significantly at p<0.05 by Duncan’s multiple range test
^A-E: Means with different superscripts in the same column differ significantly at p<0.05 by Duncan’s multiple range test