Table 1 Experimental results and SN ratio according to orthogonal array with control factors and levels

No.	Inner array				DH (%)			SN1	NR (%)			SN2	Yields (%)			SN3
	Pressure (MPa)	Temp. (°C)	Time (h)	Enzyme1) (%)	R1	R2	R3		R1	R2	R3		R1	R2	R3
1	50	40	12	0	13.99	15.23	13.56	23.05	40.30	40.68	39.30	32.06	86.30	44.77	62.39	35.28
2	50	50	24	1	18.25	19.89	20.01	25.73	58.15	60.03	59.67	35.46	74.15	58.40	63.35	36.17
3	50	60	48	2	18.33	18.23	18.96	25.34	53.20	52.60	51.80	34.41	67.76	58.66	66.23	36.10
4	75	40	24	2	25.40	23.10	23.96	27.64	70.12	68.15	69.30	36.80	70.91	81.28	78.23	37.66
5	75	50	48	0	20.12	19.38	21.85	26.18	61.35	65.55	58.14	35.77	50.34	64.38	65.26	35.37
6	75	60	12	1	28.32	27.32	29.63	29.06	80.23	81.01	81.96	38.18	71.94	90.62	72.45	37.73
7	100	40	48	1	24.99	26.35	25.36	28.15	76.70	76.08	79.05	37.76	47.99	79.97	62.56	35.50
8	100	50	12	2	27.82	25.68	25.36	28.37	78.85	76.08	77.04	37.76	98.62	88.99	78.23	38.83
9	100	60	24	0	21.02	20.05	21.52	26.38	62.59	64.56	60.15	35.90	75.58	67.26	68.23	36.91

Mixed enzyme (Alcalase^® 2.4 L:Flavourzyme^TM = 1:5).