오가피 부위별 열수 추출액의 기능적 특성

최재명², 김광엽², 이상화³, 안준배¹^,^*

Functional Properties of Water Extracts from Different Parts of Acanthopanax sessiliflorus

Jae-Myoung Choi², Kwang-Yup Kim², Sang-Hwa Lee³, Jun-Bae Ahn¹^,^*

¹서원대학교 외식산업학과

²충북대학교 식품공학과

³서원대학교 식품영양학과

¹Department of Food Service Industry, Seowon University

²Department of Food Science and Technology, Chungbuk National University

³Department of Food and Nutrition, Seowon University

^*Corresponding author: Jun-Bae Ahn, Dept. of Food Service Industry, Seowon University, 231 Mochung-dong, Heungduk-gu, Cheongju, Chungbuk 361-742, Republic of Korea, Tel: +82-43-299-8461; Fax: +82-43-299-8460, E-mail: given@seowon.ac.kr

ⓒ Copyright 2011 Korean Society for Food Engineering. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Mar 15, 2011; Revised: Apr 27, 2011; Accepted: Apr 27, 2011

Published Online: May 31, 2011

Abatract

Acanthopanax sessiliflorus (A. sessiliflorus) has been known as a traditional medicine having anti-stress, antioxidative and platelet aggregation inhibitory effects. This study was undertaken to investigate the functional properties of water extracts from four parts of A. sessiliflorus. Root, stem, leaf and fruit extracts from A. sessiliflorus were prepared with hot water (80°C). The contents of functional substances, eleutheroside B and E, polyphenol, antioxidative activity, nitrite scavenging ability and anti-cancer activity of the extracts were determined. The contents of eleutheroside E in stem, root and fruit extracts were 542.50 μg/g, 343.35 μg/g and 30.78 μg/g, respectively. A large part of eleutheroside B was found in fruit (372.01 μg/g) and root (289.33 μg/g) extracts. Root and stem extracts contained 227.21 mg/100g and 131.22 mg/100g of polyphenols, respectively. Antioxidative activities (electron donating ability) of stem and root extracts were 79.87% and 77.27%, respectively. It appears that the antioxidative activities were related to polyphenol contents of the extracts. Most extracts showed 76-81.5% of nitrite scavenging ability at pH 1.2. It reveals that water extract from parts of A. sessiliflorus can inhibit formation of nitrosoamine in food. Effects of the extracts on the growth of normal and cancer cell lines were investigated. Extracts showed no cytotoxicity to normal dendritic cell line (DC2.4). Especially, the root extract promoted the growth of normal cell line. Root and stem extracts had 20-23% of inhibitory effect against stomach cancer cell line (SNU-719) and liver cancer cell line (Hep3B). These result indicated that the extracts from A. sessiliflorus can be used as functional food materials with antioxidative activity and nitrite scavenging ability to eliminate nitrosoamine in food.

Keywords: Acanthopanax sessiliflorus; electron donating ability; nitrite scavenging ability; anti-cancer